According to the article, elevated GnRH (gonadotropin releasing hormone) levels extend the lives of mice by 10% to 100% over normal control mice with normal levels of GnRH. The article state that a chemical called NF-kB shortens the lives of mice by reducing the level of GnRH.
NF-kB is a transcription factor -- a DNA binding protein that recognizes a specific DNA sequence and binds to it -- and in the case of GnRH, negatively regulates the expression of the GnRH gene. The negative regulation reduces GnRH levels and shortens the lives of mice.
The study blocks the effects of NF-kB by taking advantage of natural inhibitors of NF-kB call IkBs. These IkB mask the protein signal that sends NF-kB into the nucleus where it bind to the GnRH gene. Since the NF-kB can't get into the nucleus, it can't down regulate GnRH so the GnRH levels remain high and the mice live longer.
It's an example of a transcriptional network (transcription is the copying of DNA into messenger RNA which is the template for proteins) that regulates aging, obesity, neuronal cell survival, diabetes, fertility, and in other settings, inflammation. NF-kB is a major intermediary in multiple diverse biological processes.
So we are all going to look beautiful and young. No selling out of souls like Dorian Gray had to do. Just understanding the nature that is in us.