EatTheRich
President
How to Conquer Coronavirus: Top 35 Treatments in Development
A new survey by Genetic Engineering & Biotechnology News (GEN) reveals 35 active drug development programs in North America, Europe and China.
www.genengnews.com
Kaletra (U.S.) ... originally developed for HIV/AIDS. Combination of lopinavir, which inhibits viral breakdown of proteins, and ritonavir, which inhibits production of enzymes that break down lopinavir, allowing it to be administered in safer doses. Lopinavir also shows experimental evidence of effectiveness against HPV while ritonavir is used against Hepatitis C. Weak evidence of effectiveness against other coronaviruses, performed poorly in U.S. clinical trials but used in conjunction with other drugs in China, S. Korea, N. Korea, Japan, Cuba, and Venezuela. Ritonavir in conjunction with another medication is in clinical trials in Switzerland.
Ampligen (U.S.): originally developed and used based on weak evidence of effectiveness in Argentina for chronic fatigue syndrome. Stimulates immune system recognition of pathogens. Petitioning China to allow clinical trials.
APN01 (Austria): developed for Coronavirus. Stimulates body to lower blood pressure and repair lung damage. Clinical trials in China.
Ganovo (U.S.): originally developed for Hepatitis C. Disrupts viral breakdown of proteins. Used in conjunction with other drugs in China and S. Korea
Heferon (Cuba): developed for hepatitis, also used for cancer. Stimulates cellular immune response. Used in Cuba, China, Japan, S. Korea, N. Korea, Venezuela, Russia, France, UK, and Germany.
ASC-09 (China): originally developed for HIV/AIDS. Disrupts viral breakdown of proteins. Clinical trials in China.
Tamiflu (U.S.): originally developed for influenza. keeps virus particles from escaping infected cells. Clinical trials in China.
Resochin (U.S.): quinine derivative. Originally developed for malaria. Also used for arthritis. Mechanism of action in this case is inhibiting virus from infecting cells and also possibly preventing viral reproduction in infected cells. Used in China and S. Korea. Clinical trials in U.S.
IFX-1 (China): developed for Coronavirus. Targets and kills Coronavirus particles. In clinical trials for Coronavirus and various skin disorders in China.
BCX4430 (U.S.): developed for influenza. prevents viral reproduction. Also used for many other viral infections. In use in S. Korea.
BXT-25 (U.S.): developed for suffocation. Gets oxygen to cells when the flow of blood is cut off. Experimental stage.
CYNK-001 (U.S.): developed for Coronaviruses, though not this one. Targets and kills infected cells before viruses can reproduce. Clinical trials in U.S., seeking clinical trials in China.
Tocilizumab (China): developed for Coronavirus. Regulates immune activity to make the immune system more effective. Clinical trials in China.
Leronlimab (U.S.): developed for Coronavirus. Also used for cancer and HIV. Targets and kills viruses. Clinical trials in U.S. and China.
Avifan (Japan): developed for Ebola. Also used for influenza. Prevents viruses from synthesizing proteins. Clinical trials in China.
Remdesivir (U.S.): developed for Ebola. Also used for Marburg, MERS, SARS, and other hemorrhagic and respiratory viruses. Prevents viruses from synthesizing proteins. Used in S. Korea, clinical trials in U.S., China, and Japan.
Camrelizumab (China): developed for cancer (carcinoma, also used for other cancers). Prevents immune system from relaxation response. Seeking clinical trials in China.
Thymosin (U.S.): developed for complications for skin punctures. Primarily used for hair loss, and illicitly as sports doping agent. Stimulates reproduction of healthy cells. Seeking clinical trials in China.
Brilacidin (U.S.): developed for cancers of the head and neck. Disrupts the protein shells of viruses. Experimental phase.
Prezcovix (U.S.): developed for HIV. Combination of darunavir, which prevents viral replication, and cobicistat, which inhibits production of enzymes by the liver, allowing more darunavir to enter the bloodstream and allowing higher doses of darunavir to be administered. Clinical trials in China.
Arbidol (Russia): developed for influenza. Prevents viruses from infecting cells. Clinical trials in Russia and China.
REGN3048(U.S.): developed for Coronavirus. Hunts down and kills Coronavirus. Experimental stage.
REGN3051 (U.S.): developed for Coronavirus. Hunts down and kills Coronavirus cells. Experimental stage.
Last edited: