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Scientists Create Antibody That Defeats Coronavirus in Lab
Scientists created a monoclonal antibody that can defeat the new coronavirus in the lab, an early but promising step in efforts to find treatments and curb the pandemic’s spread.
The experimental antibody has neutralized the virus in cell cultures. While that’s early in the drug development process -- before animal research and human trials -- the antibody may help prevent or treat Covid-19 and related diseases in the future, either alone or in a drug combination, according to a study published Monday in the journal Nature Communications.
More research is needed to see whether the findings are confirmed in a clinical setting and how precisely the antibody defeats the virus, Berend-Jan Bosch of Utrecht University in the Netherlands and colleagues wrote in the paper.
The antibody known as 47D11 targets the spike protein that gives the new coronavirus a crown-like shape and lets it enter human cells. In the Utrecht experiments, it didn’t just defeat the virus responsible for Covid-19 but also a cousin equipped with similar spike proteins, which causes Severe Acute Respiratory Syndrome, or SARS.
Complete text: https://www.bloomberg.com/news/arti...eate-antibody-that-defeats-coronavirus-in-lab
Also:
www.nature.com
www.scienceboard.net
I believe most will see this as a positive development.
Scientists Create Antibody That Defeats Coronavirus in Lab
Scientists created a monoclonal antibody that can defeat the new coronavirus in the lab, an early but promising step in efforts to find treatments and curb the pandemic’s spread.
The experimental antibody has neutralized the virus in cell cultures. While that’s early in the drug development process -- before animal research and human trials -- the antibody may help prevent or treat Covid-19 and related diseases in the future, either alone or in a drug combination, according to a study published Monday in the journal Nature Communications.
More research is needed to see whether the findings are confirmed in a clinical setting and how precisely the antibody defeats the virus, Berend-Jan Bosch of Utrecht University in the Netherlands and colleagues wrote in the paper.
The antibody known as 47D11 targets the spike protein that gives the new coronavirus a crown-like shape and lets it enter human cells. In the Utrecht experiments, it didn’t just defeat the virus responsible for Covid-19 but also a cousin equipped with similar spike proteins, which causes Severe Acute Respiratory Syndrome, or SARS.
Complete text: https://www.bloomberg.com/news/arti...eate-antibody-that-defeats-coronavirus-in-lab
Also:
A human monoclonal antibody blocking SARS-CoV-2 infection - Nature Communications
Vaccines and targeted therapeutics for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are currently lacking. Here, the authors report a human monoclonal antibody capable of neutralizing both authentic SARS-CoV and SARS-CoV-2 by targeting a common epitope.
www.nature.com
Researchers investigate how a potent mAb blocks SARS-CoV-2
Based on previous research that explored therapies against SARS-CoV, a new report has identified a fully human monoclonal antibody (mAb) that prevents the SARS-CoV-2 virus from infecting cultured cells. Authored by a team of researchers from Utrecht University, Erasmus Medical Center, and...
I believe most will see this as a positive development.
